Abstract: The microstructure, tensile properties, Charpy impact properties and fatigue behavior at 350 ℃ of SA533B steel plates for nuclear power plant equipments were analyzed. The results show that the microstructure of SA533B steel plates was fine and homogeneous granular bainite, and was normal quenched and tempered microstructure. The steel plates had excellent general mechanical properties, had high strength, plasticity, impact toughness and fatigue properties at the same time, and conformed to the requirements for reactor design.